Insulin resistance, a key factor in the risk of developing Alzheimer's disease
A team led by Mònica Bulló, Director of the NuMeH Research Group and the TecnATox center, with the collaboration of researchers from the Pere Virgili Health Research Institute, the Ace Alzheimer Center Barcelona, the Pablo de Olavide University of Seville, and the ITAKA research group from URV, also part of TecnATox, has identified 18 metabolites in the blood that link insulin resistance with a higher risk of developing Alzheimer's disease. This discovery improves the prediction of the disease and opens new avenues for designing preventive and therapeutic strategies.
Reference: Laia Gutierrez-Tordera, Laura Panisello, Pablo García-Gonzalez, Agustín Ruiz, José Luis Cantero, Melina Rojas-Criollo, Muhammad Mursil, Mercedes Atienza, Nil Novau-Ferré, Javier Mateu-Fabregat, Hamza Mostafa, Domènec Puig, Jaume Folch, Hatem Rashwan, Marta Marquié, Mercè Boada, Christopher Papandreou, Mònica Bulló, Metabolic signature of insulin resistance and risk of Alzheimer's disease, The Journals of Gerontology: Series A, 2024;, glae283, https://doi.org/10.1093/gerona/glae283
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